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Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia

Friedreich ataxia (FRDA) is a devastating neurodegenerative disease caused by mutations in the frataxin gene (FXN). Frataxin is an essential protein which localizes to the mitochondria and is required for the synthesis of iron-sulfur clusters and heme. Most individuals with FRDA are homozygous for trinucleotide

Read More: Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia


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Jen Farmer

Jen Farmer

Executive Director

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