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FARAFARA Cure FA

HSC20 interacts with Frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis

Friedreich's ataxia is a neurodegenerative disorder caused by mutations in the frataxin gene that produces a predominantly mitochondrial protein whose primary function appears to be mitochondrial iron-sulfur cluster (ISC) biosynthesis. Previously we demonstrated that frataxin interacts with multiple components of the mammalian ISC assembly machinery.

HSC20 interacts with Frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis


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Jen Farmer

Jen Farmer

Executive Director

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