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Analysis of the structural and mechanistic factors in antioxidants that preserve mitochondrial function and confer cytoprotection

Selected pyridinol analogues of the experimental neuroprotective drug idebenone have been synthesized and evaluated as antioxidants capable of preserving mitochondrial function. The compounds, having a different redox core but the same side chain as idebenone, exhibited a range of potencies, reflecting differences in their structures.

Read More: Analysis of the structural and mechanistic factors in antioxidants that preserve mitochondrial function and confer cytoprotection

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