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The Neuropathology of Late-Onset Friedreich's Ataxia

Friedreich's ataxia (FRDA) affects very young persons. In a large series, the mean ages of onset and death were 11 and 38 years, respectively. The clinical spectrum of FRDA has expanded after genetic confirmation of the mutation became a routine laboratory test. The main cause of death in juvenile-onset FRDA is cardiomyopathy whereas patients with late-onset are more likely to succumb to neurological disability or an intercurrent illness.

The Neuropathology of Late-Onset Friedreich's Ataxia

About the Author

Jen Farmer

Jen Farmer

Executive Director


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