OBJECTIVES:

To evaluate the relationship between disease features in Friedreich ataxia and aberrant glucose metabolism.

METHODS:

Fasting glucose, fasting insulin and random HbA1C were obtained in 158 patients with Friedreich ataxia. Regression analysis evaluated glucose, insulin, and homeostatic model assessment (HOMA) of insulin resistance (IR) and beta-cell function (ß) in relation to age, BMI, sex, and genetic severity. Categorical glucose values were analyzed in relation to other FRDA-associated disease characteristics.

Read More: Cross-sectional analysis of glucose metabolism in Friedreich Ataxia