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FARAFARA Cure FA

Frataxin knockdown in human astrocytes triggers cell death and the release of factors that cause neuronal toxicity

Friedreich's ataxia (FA) is a recessive, predominantly neurodegenerative disorder caused in most cases by mutations in the first intron of the frataxin (FXN) gene. This mutation drives the expansion of a homozygous GAA repeat that results in decreased levels of FXN transcription and frataxin protein.

Read More: Frataxin knockdown in human astrocytes triggers cell death and the release of factors that cause neuronal toxicity


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Jen Farmer

Jen Farmer

Executive Director

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