Accept Cookies?
Provided by OpenGlobal E-commerce

Please wait while your page loads ...

FARAFARA Cure FA

Regional Cerebral Disease Progression in Friedreich's Ataxia: A Longitudinal Diffusion Tensor Imaging Study

J Neuroimaging. 2015 Jul 14. doi: 10.1111/jon.12270. [Epub ahead of print] Mascalchi M, Toschi N, Giannelli M, Ginestroni A, Della Nave R, Tessa C, Piacentini S, Dotti MT, Aiello M, Nicolai E, Soricelli A, Salvi F, Diciotti S
 

We explored the potential of brain MR morphometry and diffusion tensor imaging (DTI) to track the progression of neurodegeneration in FRDA. Longitudinal analyses showed no differences in regional volume changes but a significant difference in axial diffusivity changes in cerebral and corpus callosum WM of patients as compared to controls (mean longitudinal rate of change for axial diffusivity: -.02 × 10-3 mm2 /s/year in patients vs. .01 × 10-3 mm2 /s/year in controls). No correlation with number of triplets, disease duration, and worsening of the clinical deficit was observed.

Read More:  Regional Cerebral Disease Progression in Friedreich's Ataxia: A Longitudinal Diffusion Tensor Imaging Study

 

 


About the Author

Jen Farmer

Jen Farmer

Executive Director

SHARE

FacebookTwitterLinkedinShare on Google+
Science C.jpg

 

Archived in
  Scientific News


 

 

Tagged in
FARA Scientific News