The goal of this project is to create technologies that can sensitively identify and measure progression of motor changes in Friedreich’s ataxia (FA). These technologies would support early detection of FA signs and symptoms and facilitate drug development efforts by providing objective and sensitive digital measures for use as endpoints in clinical trials in FA, including early-stage disease.
In 2025, Neurobooth started a new project focused on FA. Individuals who previously participated in a Neurobooth study may be eligible to join this new study.
Anyone considering participating in a clinical trial should discuss the matter with their physician. FARA does not endorse or recommend any particular studies.
Study Details:
Neurobooth uses many digital devices to quickly collect information about motor and cognitive symptoms. It then uses machine learning and Artificial Intelligence algorithms to gain insights about disease and produce measures for clinical trials.
Participants will be guided through a set of neurological tasks while wearing lightweight, non-invasive sensors. These tasks include tracking objects with your eyes, solving puzzles on a computer screen, speaking words aloud, moving your arms and legs, and walking back and forth down a hallway. During this time, we will be recording your movement and speech with cameras, eye tracking devices, and microphones. Participants will also undergo a clinician-performed neurological examination. At home participants will complete surveys on daily function and quality of life.
Participants will be compensated $100 for each visit. Reimbursement for parking and travel costs (airfare and one night of lodging) up to $800 will also be provided.
Key Inclusion Criteria:
- Individuals with FA who are 8-30 years old, with or without symptoms
- Healthy controls without a neurological or musculoskeletal condition or other condition that affects movement or thinking
- Ability to walk with or without an assistive device
Additional inclusion and exclusion criteria may apply and will be evaluated by a study doctor.
Length of Study Commitment:
This study involves visits every six months for a total of four visits.