FUNDING FA RESEARCH

Grant Program

FARA supports research through funding competitive grants across the spectrum from basic research through drug development and clinical research programs in Friedreich’s ataxia (FA). FARA promotes collaboration among scientists, advocates for public-private partnerships, and hosts open forums for leading scientists to share their insights and ideas to advance therapeutic development for FA.

All investigators interested in FA-related research are invited to submit a Letter of Intent (LOI) through FARA’s grant submission portal. All proposed research must fall within FARA’s Grant Program Priorities.

FARA-Funded Grants

FUNDED GRANT | Dec 2026

Defining new epigenetic gene silencing axis driving repeat-associated heterochromatin formation in Friedreich’s Ataxia patients’ cells 

Graduate Research Fellowship, Mechanism or Pathway of Disease Remi Neplaz,
Universite Claude Bernard Lyon, Villeurbanne, France
FUNDED GRANT | Nov 2026

Defining and targeting cardiac lipid dysregulation in Friedreich ataxia using human iPSC-derived cardiac models 

General Research Grant, Outcome Measures & Biomarkers Jarmon Lees, Ph.D.,
St. Vincent's Institute of Medical Research, Victoria, Australia
FUNDED GRANT | Sep 2026

Tunable genetic circuits to enable precision genetic medicines for Friedreich's Ataxia

Award for Innovative Mindset (AIM), Drug Discovery Nicholas Goeden, PhD,
Asymptote Genetic Medicines Inc, Pasadena, CA
FUNDED GRANT | Sep 2026

CBM-01, A Novel Inhibitor of Lipid Peroxidation for Targeting Iron-mediated Pathology in FA Cardiomyopathy  

General Research Grant, Drug Discovery Vasanthi Viswanathan, Ph.D.,
Coastline Biomedicine, Boston, MA
FUNDED GRANT | Sep 2026

Investigating molecular mechanisms underlying microglia hyperactivation in Friedreich Ataxia 

Postdoctoral Research Award, Mechanism or Pathway of Disease Carla Pernaci, Ph.D.,
Sanford Consortium for Regenerative Medicine, La Jolla, CA
FUNDED GRANT | Sep 2026

Activation of the ZBP1–cGAS–STING–Type I Interferon Axis as a Mechanistic Driver of Cardiomyopathy in Friedreich’s Ataxia 

Postdoctoral Fellowship, Mechanism or Pathway of Disease Gaomin Feng, Ph.D.,
The Jackson Laboratory, Bal Harbor, ME
FUNDED GRANT | Sep 2026

Investigating Synthetic Gene Regulator function in FRDA patient-derived Cardiomyocytes and neuronal cell types

Postdoctoral Research Award, Drug Discovery Kumari Sweta, Ph.D,
St. Jude Children's Research Hospital, Memphis, TN
FUNDED GRANT | Feb 2026

SHIFT-FA – Study of Heterogeneity in Friedreich’s Ataxia Trajectories

Postdoctoral Research Award, Mechanism or Pathway of Disease Isabell Cordts, MD,
University of Munich, Friedrich-Baur-Institut
FUNDED GRANT | Feb 2026

Investigating spinal sensory-motor circuit pathology in two mouse models of FA

Postdoctoral Fellowship, Mechanism or Pathway of Disease Nicholas Stachowski, PhD,
Children's Hospital of Philadelphia
FUNDED GRANT | Feb 2026

AIMs_Play: Predicting Disease Progression in Pediatric Friedreich Ataxia with Generative AI-Enabled Platform

General Research Grant, Outcome Measures & Biomarkers Pubudu Pathirana, PhD, and Louise Corben, PhD,
Deakin University and Murdoch Children’s Research Institute
FUNDED GRANT | Feb 2026

Neuro-otology: Diffusion MRI and audiological biomarkers for Friedreich ataxia disease progression

General Research Grant, Outcome Measures & Biomarkers Julien Zanin, PhD,
University of Melbourne
FUNDED GRANT | Jan 2026

RNA Writing Trans-Splicing for Enhancing Frataxin Translation

General Research Grant, Gene & Stem Cell Therapy Jonathan Gootenberg, PhD, and Omar Abudayyeh, PhD,
Beth Israel Deaconess Medical Center and Brigham and Women’s Hospital
TOOLS FOR FOR RESEARCHERS & INDUSTRY

Research Resources

FARA provides valuable resources designed to support industry partners and researchers dedicated to advancing research and development for FA. Whether you’re a seasoned researcher or a new entrant to the field, FARA can offer tools to build the foundation you need to make significant contributions to the FA research landscape.

ADVANCING RESEARCH AND THERAPEUTIC DEVELOPMENT

Research Initiatives

FARA’s research initiatives are organized efforts aimed at advancing knowledge about FA through research. These initiatives put the patient voice in the forefront and focus on collaboration between researchers across countries and continents, bridging gaps in knowledge to benefit all stakeholders.

FARA funds FA research through 3 different mechanisms: the grant program, institutional supported programs and FARA directed projects. FARA believes the sum of these initiatives to be most impactful in advancing research and therapeutic development. The goal is to drive the science, facilitate access to resources, promote collaboration among FA investigators and encourage public/private partnerships.

Learn More About FARA's Research Initiatives

FA Global Clinical Consortium

FARA Directed Research

Institutional Supported Programs

PROGRESS OF RESEARCH AND DEVELOPMENT ON LEAD THERAPEUTIC CANDIDATES

Drug Development Pipeline

FARA supports the advancement of treatments with financial resources, advocacy, patient engagement and/or fostered collaboration. FARA believes that there is merit in each of these approaches and that effective treatment of FA will come in the form of a "cocktail approach" – a combination of two or more therapies.

This pipeline focuses on drugs that are already in preclinical development or have advanced to human clinical trials, and descriptions are updated regularly as new information becomes available.

Drug Development Pipeline
drug development pipeline
PLAY A ROLE IN THE SEARCH FOR TREATMENTS AND CURES

Participate in Research

Participation in FA research directly influences the treatments that reach those living with FA, potentially shortening the timeline for access to life-changing advancements.

Clinical trials are the final step before therapies reach the wider community, making them an important step on the journey to slow, stop, reverse, and cure FA.

Young girl in hospital