FUNDING FA RESEARCH

Grant Program

FARA supports research through funding competitive grants across the spectrum from basic research through drug development and clinical research programs in Friedreich’s ataxia (FA). FARA promotes collaboration among scientists, advocates for public-private partnerships, and hosts open forums for leading scientists to share their insights and ideas to advance therapeutic development for FA.

All investigators interested in FA-related research are invited to submit a Letter of Intent (LOI) through FARA’s grant submission portal. All proposed research must fall within FARA’s Grant Program Priorities.

FARA-Funded Grants

FUNDED GRANT
| Mar 2024

Treatment of Friedreich’s ataxia using novel ferroptosis inhibitors

General Research Grant, Lead Candidates Brent R. Stockwell, PhD,
Columbia University
FUNDED GRANT
| Jan 2024

Deciphering the neurodevelopmental component in Friedreich Ataxia

Graduate Research Fellowship, Mechanism or Pathway of Disease Lucie Hermet,
Institute NeuroMyoGène, Lyon, France
FUNDED GRANT
| Dec 2023

Modelling Friedreich Ataxia in human iPSC-derived cerebellar organoids

General Research Grant, Cell & Animal Models Esther Becker, PhD,
University of Oxford
FUNDED GRANT
| Nov 2023

Anatomical and functional analysis of corticospinal tract in FRDA mouse model

Postdoctoral Fellowship, Mechanism or Pathway of Disease Misa Nishiyama, PhD,
Burke Neurological Institute
FUNDED GRANT
| Oct 2023

Role of the Thromboxane-Prostanoid Receptor in FRDA Cardiomyopathy

General Research Grant, Cardiac Research Mark Payne, MD,
Indiana University School of Medicine
FUNDED GRANT
| Oct 2023

Hematopoietic Stem Cell Transplantation in FRDA: Proof-of-concept studies using novel conditioning regimen and the YG8s(GAA)>800 mouse

Postdoctoral Research Award, Gene & Stem Cell Therapy Hynmin Cho, PhD,
Stanford University
FUNDED GRANT
| Sep 2023

Elucidation of the peripheral immune axis in FRDA and identification of blood-based biomarkers of inflammation

Graduate Research Fellowship, Outcome Measures & Biomarkers Shweta Sahni,
All India Institute of Medical Sciences (AIIMS), New Delhi
FUNDED GRANT
| Sep 2023

A tractable vertebrate model that recapitulates key aspects of Friedreich Ataxia

General Research Grant, Cell & Animal Models Robert Wilson, MD, PhD,
Children’s Hospital of Philadelphia
FUNDED GRANT
| Sep 2023

Population and cellular heterogeneity in Friedreich Ataxia

Graduate Research Fellowship, Mechanism or Pathway of Disease Morgan Tackett,
University of Oklahoma Health Sciences Center
FUNDED GRANT
| Sep 2023

Investigating the effects of frataxin deficiency on the human proteome

Graduate Research Fellowship, Mechanism or Pathway of Disease Angela Xiong,
Boston College
FUNDED GRANT
| Sep 2023

Mechanism of neuronal rescue by microglia expressing frataxin and characterization of neuronal defects in Friedreich’s ataxia

General Research Grant, Mechanism or Pathway of Disease Stephanie Cherqui, PhD and Nicole Coufal, MD, PhD,
University of California, San Diego
FUNDED GRANT
| Sep 2023

AAV-mediated therapy for visual impairment associated with Friedreich's Ataxia

General Research Grant, Gene & Stem Cell Therapy Shannon Boye, PhD,
University of Florida
TOOLS FOR FOR RESEARCHERS & INDUSTRY

Research Resources

FARA provides valuable resources designed to support industry partners and researchers dedicated to advancing research and development for FA. Whether you’re a seasoned researcher or a new entrant to the field, FARA can offer tools to build the foundation you need to make significant contributions to the FA research landscape.

ADVANCING RESEARCH AND THERAPEUTIC DEVELOPMENT

Research Initiatives

FARA’s research initiatives are organized efforts aimed at advancing knowledge about FA through research. These initiatives put the patient voice in the forefront and focus on collaboration between researchers across countries and continents, bridging gaps in knowledge to benefit all stakeholders.

FARA funds FA research through 3 different mechanisms: the grant program, institutional supported programs and FARA directed projects. FARA believes the sum of these initiatives to be most impactful in advancing research and therapeutic development. The goal is to drive the science, facilitate access to resources, promote collaboration among FA investigators and encourage public/private partnerships.

Learn More About FARA's Research Initiatives

FA Global Clinical Consortium

FARA Directed Research

Institutional Supported Programs

PROGRESS OF RESEARCH AND DEVELOPMENT ON LEAD THERAPEUTIC CANDIDATES

Drug Development Pipeline

FARA supports the advancement of treatments with financial resources, advocacy, patient engagement and/or fostered collaboration. FARA believes that there is merit in each of these approaches and that effective treatment of FA will come in the form of a "cocktail approach" – a combination of two or more therapies.

This pipeline focuses on drugs that are already in preclinical development or have advanced to human clinical trials, and descriptions are updated regularly as new information becomes available.

Drug Development Pipeline
drug development pipeline
PLAY A ROLE IN THE SEARCH FOR TREATMENTS AND CURES

Participate in Research

Participation in FA research directly influences the treatments that reach those living with FA, potentially shortening the timeline for access to life-changing advancements.

Clinical trials are the final step before therapies reach the wider community, making them an important step on the journey to slow, stop, reverse, and cure FA.

Young girl in hospital