APPLY FOR A FARA RESEARCH GRANT

General Research Grant Deadlines and Budget Limits

Grant TypeLetter of Intent (LOI) DeadlineApplication DeadlineAward NoticeGrant Start DatesMaximum Budget (USD)

General Research Grant

Feb 15
Aug 15

Apr 15
Oct 15

Aug 1
Feb 1

Sep 1 – Oct 1
Mar 1 – Apr 1

$125,000 per year for 1 or 2 years

Award for Innovative Mindset (AIM)

No LOI

Feb 1

May 1

Jun 1 – Jul 1

$100,000 for 1 year

Keith Michael Andrus Cardiac Award

Nov 1

Feb 1

Jun 1

Jul 1 – Aug 1

$150,000 per year for 1 or 2 years

Kyle Bryant Translational Research Award

Nov 1

Feb 1

Jun 1

Jul 1 – Aug 1

$250,000 per year for 1 or 2 years

Bronya J. Keats Research Collaboration Award

Nov 1

Feb 1

Jun 1

Jul 1 – Aug 1

$200,000 per year for 1 or 2 years

Postdoctoral Research Award

Feb 15
Aug 15

Apr 15
Oct 15

Aug 1
Feb 1

Sep 1 – Oct 1
Mar 1 – Apr 1

$100,000 per year for 1 or 2 years

Postdoctoral Fellowship

Feb 15
Aug 15

Apr 15
Oct 15

Aug 1
Feb 1

Sep 1 – Oct 1
Mar 1 – Apr 1

Trainee salary up to 2 years

Graduate Research Fellowship

Mar 15

May 15

Sep 1

Oct 1 – Nov 1

$50,000 per year up to 3 years

Request for Proposals and Ad-hoc Requests

TBC

General Research Grant

The General Research Grant is open to qualified investigators proposing projects that align with FARA Research Priorities.

Maximum Budget (USD): $125,000 per year for 1 or 2 years

1st Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Feb 15
  • Application Deadline: Apr 15
  • Award Notice: Aug 1
  • Grant Start Dates: Sep 1 – Oct 1

2nd Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Aug 15
  • Application Deadline: Oct 15
  • Award Notice: Feb 1
  • Grant Start Dates: Mar 1 – Apr 1
FUNDED GRANTS

General Research Grants

FUNDED GRANT
| Mar 2024

Treatment of Friedreich’s ataxia using novel ferroptosis inhibitors

General Research Grant, Lead Candidates Brent R. Stockwell, PhD,
Columbia University
FUNDED GRANT
| Dec 2023

Modelling Friedreich Ataxia in human iPSC-derived cerebellar organoids

General Research Grant, Cell & Animal Models Esther Becker, PhD,
University of Oxford
FUNDED GRANT
| Oct 2023

Role of the Thromboxane-Prostanoid Receptor in FRDA Cardiomyopathy

General Research Grant, Cardiac Research Mark Payne, MD,
Indiana University School of Medicine
FUNDED GRANT
| Sep 2023

A tractable vertebrate model that recapitulates key aspects of Friedreich Ataxia

General Research Grant, Cell & Animal Models Robert Wilson, MD, PhD,
Children’s Hospital of Philadelphia
FUNDED GRANT
| Sep 2023

Mechanism of neuronal rescue by microglia expressing frataxin and characterization of neuronal defects in Friedreich’s ataxia

General Research Grant, Mechanism or Pathway of Disease Stephanie Cherqui, PhD and Nicole Coufal, MD, PhD,
University of California, San Diego
FUNDED GRANT
| Sep 2023

AAV-mediated therapy for visual impairment associated with Friedreich's Ataxia

General Research Grant, Gene & Stem Cell Therapy Shannon Boye, PhD,
University of Florida
FUNDED GRANT
| Jun 2023

Identification of concordant electrophysiological biomarkers in Friedreich Ataxia

General Research Grant, Mechanism or Pathway of Disease Donald Joseph, PhD,
Children's Hospital of Philadelphia
FUNDED GRANT
| Jul 2023

Discovery of frataxin substitute drug candidates for the treatment of Friedreich's Ataxia

General Research Grant, Drug Discovery Benoit D'Autréaux, PhD,
CNRS-CEA-Université Paris-Saclay, France
FUNDED GRANT
| Jun 2023

Trojan nanobodies to increase frataxin function

General Research Grant, Drug Discovery Javier Santos, PhD,
University of Buenos Aires, Argentina
FUNDED GRANT
| Mar 2023

An optimized deep learning-based method for cerebellum segmentation

General Research Grant, Outcome Measures & Biomarkers Thiago Rezende, PhD & Ian Harding, PhD,
Monash University, Australia
FUNDED GRANT
| Mar 2023

Mechanism of repeat expansion in Friedreich's ataxia

General Research Grant, Mechanism or Pathway of Disease Andre Nussenzweig, PhD,
National Cancer Institute, NIH
FUNDED GRANT
| Mar 2023

An induced pluripotent stem cell model to investigate microglia in Friedreich Ataxia

General Research Grant, Mechanism or Pathway of Disease Massimo Pandolfo, MD and Stefano Stifani, PhD,
McGill University

Award for Innovative Mindset (AIM)

The Award for Innovative Mindset (AIM) supports the initial exploration of innovative, high-risk, high-gain, and potentially ground-breaking concepts in FA research, that will foster new directions, bring new perspectives to the field and address neglected issues in FA research. The presentation of preliminary and/or published data is encouraged, but not required.

Studies supported by this award mechanism are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on strong scientific rationale and study design.

Research that is an incremental advance upon published data is not consistent with the intent of this award mechanism. It is the responsibility of the Principal Investigator (PI) to clearly and explicitly articulate how the proposed research project is innovative in the field of FA.

Maximum Budget (USD): $100,000 for 1 year

Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: N/A
  • Application Deadline: Feb 1
  • Award Notice: May 1
  • Grant Start Dates: Jun 1 – Jul 1
FUNDED GRANTS

Award for Innovative Mindset (AIM)

FUNDED GRANT
| Jul 2023

Uncovering the function of a conserved site in eukaryotic frataxins

Award for Innovative Mindset (AIM), Mechanism or Pathway of Disease Jordi Tamarit, PhD,
Universitat de Lleida, Spain
FUNDED GRANT
| Jun 2023

Measurement of Frataxin mRNA in NHP and human biofluids

Award for Innovative Mindset (AIM), Outcome Measures & Biomarkers Eric Wang, PhD & S.H. Subramony, MD,
University of Florida
FUNDED GRANT
| Dec 2022

TGFβ signaling activity as disease biomarkers and therapeutic targets in Friedreich’s Ataxia

Award for Innovative Mindset (AIM), Mechanism or Pathway of Disease Pei-Yu Chen, PhD,
Yale University
FUNDED GRANT
| Sep 2022

Functional electrical stimulation (FES) cycling training to improve motor and cardiac functions in patients with Friedreich’s Ataxia: a feasibility and efficacy study

Award for Innovative Mindset (AIM), Improving Clinical Outcomes Manuela Corti, PhD & Tanja Taivassalo, PhD,
University of Florida
FUNDED GRANT
| Jun 2022

A New Ultrasensitive Single-Molecule Assay for Frataxin Measurement

Award for Innovative Mindset (AIM), Outcome Measures & Biomarkers Ankur Jain, PhD & Ricardo Mouro Pinto, PhD,
Whitehead Institute for Biomedical Research, Harvard Medical School and Massachusetts General Hospital

Keith Michael Andrus Cardiac Award

The Keith Michael Andrus Cardiac Research Award was made in honor of its namesake to remember Keith’s legacy and to help advance our understanding and treatment of cardiomyopathy associated with FA. Proposals for this award should focus on advancing understanding and/or treatment of the cardiac involvement in FA.

Maximum Budget (USD): $150,000 per year for 1 or 2 years

Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Nov 1
  • Application Deadline: Feb 1
  • Award Notice: Jun 1
  • Grant Start Dates: Jul 1 – Aug 1
FUNDED GRANTS

Keith Michael Andrus Cardiac Award

FUNDED GRANT
| Dec 2022

Advancing novel mitochondrial therapies for FA cardiomyopathy: a pragmatic collaboration to move new therapies forward

Keith Michael Andrus Cardiac Award, Cardiac Research Laura Kropp, PhD, MPH,
Stealth BioTherapeutics

Kyle Bryant Translational Research Award

The Kyle Bryant Translational Research Award honors its namesake for his diligent efforts to aid in the acceleration of preclinical studies to early pilot trials in FA patients. This award is given to proposals focused on pre-clinical and clinical investigations that will advance treatments for FA.

The specific aims must target one or more of the following:

  • Identification of biomarkers for FA that will elucidate disease variability, severity, and prognosis, facilitate drug screening, and/or optimize selection of patients and clinical endpoints for clinical trials
  • Development of tools and technologies that can:
    • be directly used for therapy development;
    • overcome existing obstacles to treatment;
    • be directly applied to, or adapted for, delivery of potential therapeutics;
  • Pre-clinical development and testing of potential therapeutics, biologics, and devices in cells and animals
  • Clinical studies of patient outcome measures

Maximum Budget (USD): $250,000 per year for 1 or 2 years

Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Nov 1
  • Application Deadline: Feb 1
  • Award Notice: Jun 1
  • Grant Start Dates: Jul 1 – Aug 1
FUNDED GRANTS

Kyle Bryant Translational Research Award

FUNDED GRANT
| Aug 2022

Detection and enhancement of tissue NAD+ levels in Friedreich’s Ataxia

Kyle Bryant Translational Research Award, Outcome Measures & Biomarkers Joseph Baur, PhD & Shana McCormack, MD,
University of Pennsylvania and Children's Hospital of Philadelphia
FUNDED GRANT
| Jan 2022

Therapeutic activity of a haematopoietic stem cell delivered tissue penetrating peptide in a Friedreich's ataxia mouse model

Kyle Bryant Translational Research Award, Gene & Stem Cell Therapy Arturo Sala, PhD,
Brunel University, London

Bronya J. Keats Research Collaboration Award

The Bronya J. Keats Research Collaboration Award honors its namesake for her academic career in understanding the GAA triplet repeat mutation in FA, and her continued role in managing FARA’s grant program. Proposals should focus on FA research that relies on collaboration among investigators from at least two different institutions. Special consideration will be given to proposals that involve international collaborations and bring new scientists to the FA community. The rationale for the collaboration needs to be convincing: it must clearly demonstrate that the research goals could not be achieved by just one of the participating groups and the synergy among the groups is essential for the success of the project.

Maximum Budget (USD): $200,000 per year for 1 or 2 years

Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Nov 1
  • Application Deadline: Feb 1
  • Award Notice: Jun 1
  • Grant Start Dates: Jul 1 – Aug 1
FUNDED GRANTS

Bronya J. Keats Research Collaboration Award

FUNDED GRANT
| May 2020

Identification of genetic modifiers of Friedreich's ataxia

Bronya J. Keats Research Collaboration Award, Mechanism or Pathway of Disease Henry Houlden, MD, PhD,
University College London, UK

Postdoctoral Research Award

FARA offers a Postdoctoral Research Award as a mechanism to expand and retain young investigators in the FA biomedical research space.

For this application type, the Postdoctoral trainee is the PI of the grant proposal. Applicants must have completed at least 18 months of postdoctoral training. Eligible applicants are postdoctoral trainees with fewer than 7 years working as a postdoctoral trainee, accounting for career disruptions. Postdoctoral trainees should focus their research proposal on projects that fall within FARA Research Priorities. Applicants are required to submit a personal statement describing their current position and plans for the future as it relates to FA research, with a description of career goals and how the proposed research and research environment will favor achieving those goals. A mentoring plan developed jointly by the junior investigator and mentor(s), as well as letters of support from all mentors are also required. The only allowable budget items are the trainee’s salary/stipend, plus applicable fringe benefits, supplies and travel to conferences if adequately justified and directly related to the proposed research. The trainee is required to contribute at least 75% effort to the proposed work. Competitive candidates demonstrate qualities that will enhance FARA’s overall enterprise of understanding fundamentals of disease pathology and developing treatments and a cure for FA.

Maximum Budget (USD): $100,000 per year for 1 or 2 years

1st Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Feb 15
  • Application Deadline: Apr 15
  • Award Notice: Aug 1
  • Grant Start Dates: Sep 1 – Oct 1

2nd Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Aug 15
  • Application Deadline: Oct 15
  • Award Notice: Feb 1
  • Grant Start Dates: Mar 1 – Apr 1
FUNDED GRANTS

Postdoctoral Research Award

FUNDED GRANT
| Oct 2023

Hematopoietic Stem Cell Transplantation in FRDA: Proof-of-concept studies using novel conditioning regimen and the YG8s(GAA)>800 mouse

Postdoctoral Research Award, Gene & Stem Cell Therapy Hynmin Cho, PhD,
Stanford University
FUNDED GRANT
| Mar 2023

Repeat associated non-AUG (RAN) proteins in FA: contribution to disease and therapeutic opportunities

Postdoctoral Research Award, Mechanism or Pathway of Disease Lisa Romano, PhD, FARA Australia,
University of Florida
FUNDED GRANT
| Sep 2022

Calcium communication among intracellular compartments in FA patient-derived cells

Postdoctoral Research Award, Mechanism or Pathway of Disease Anna Stepanova, PhD,
Weill Cornell Medical College
FUNDED GRANT
| Jan 2022

Investigating epigenetic silencing in Friedreich's Ataxia

Postdoctoral Research Award, Mechanism or Pathway of Disease Rucha Sarwade, PhD,
Monash University, Australia
FUNDED GRANT
| Apr 2021

Hepcidin-Ferroportin axis in Friedreich's Ataxia

Postdoctoral Research Award, Mechanism or Pathway of Disease Elisabetta Indelicato, MD, PhD,
Medical University of Innsbruck, Austria
FUNDED GRANT
| Jun 2020

Cardiac Imaging Biomarkers in Friedreich's Ataxia

Postdoctoral Research Award, Cardiac Research Marcondes França Jr., MD, PhD & Thiago Rezende, PhD,
University of Campinas, Brazil

Postdoctoral Fellowship

FARA offers a Postdoctoral Fellowship to support young investigators in the FA biomedical research space. For this application type, the PI of the grant proposal may be either the trainee or the trainee's faculty advisor; however, both the trainee and advisor must be named in the application.

Eligible applicants are postdoctoral trainees with fewer than 6 years working as a postdoctoral trainee, accounting for career disruptions, and fewer than 4 years working in an FA lab as a postdoctoral trainee. Applicants are required to submit a personal statement describing their current position and plans for the future as it relates to FA research, with a description of career goals and how the proposed research and research environment will favor achieving those goals. A mentoring plan developed jointly by the junior investigator and mentor(s), as well as letters of support from all mentors are also required. The only allowable budget item is the trainee salary/stipend (plus applicable fringe benefits), which must not exceed the appropriate NIH stipend level. Postdoctoral trainees should provide a minimum 75% effort contributed to the design, writing and implementation of the proposed work.

Maximum Budget (USD): Trainee salary for up to two years, plus applicable fringe benefits

1st Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Feb 15
  • Application Deadline: Apr 15
  • Award Notice: Aug 1
  • Grant Start Dates: Sep 1 – Oct 1

2nd Round of Annual Funding Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: Aug 15
  • Application Deadline: Oct 15
  • Award Notice: Feb 1
  • Grant Start Dates: Mar 1 – Apr 1
FUNDED GRANTS

Postdoctoral Fellowship

FUNDED GRANT
| Nov 2023

Anatomical and functional analysis of corticospinal tract in FRDA mouse model

Postdoctoral Fellowship, Mechanism or Pathway of Disease Misa Nishiyama, PhD,
Burke Neurological Institute
FUNDED GRANT
| Jul 2023

Investigating the Mechanosensory System in Friedreich’s Ataxia using Stem Cell Models

Postdoctoral Fellowship, Mechanism or Pathway of Disease Amy Hulme, PhD,
University of Wollongong
FUNDED GRANT
| Oct 2022

Illuminating how SynGRs liberate gene expression from heterochromatin

Postdoctoral Fellowship, Mechanism or Pathway of Disease Sarah Robinson-Thiewes, PhD,
St. Jude Children's Research Hospital
FUNDED GRANT
| Oct 2022

Engineering adeno-associated viral vectors to evade immune responses

Postdoctoral Fellowship, Gene & Stem Cell Therapy Changfan Lin, PhD,
California Institute of Technology
FUNDED GRANT
| Oct 2021

Pathophysiology of Muscle Dysfunction in Friedreich's Ataxia

Postdoctoral Fellowship, Mechanism or Pathway of Disease Chen Liang, PhD,
University of Rochester

Graduate Research Fellowship

The Graduate Research Fellowship provides 1 to 3 years of support for individuals engaged in graduate study leading to a Doctor of Philosophy (Ph.D.) degree (or equivalent).

FARA will award up to 3 Graduate Research Fellowships per year. For this application type, the PI/applicant of the grant proposal is the graduate student. Applicants need to be matriculated in the chosen graduate school and have a chosen thesis adviser at the time of application. Proof of passing qualifying exam, if applicable, is required at time of application or must be provided within a year of receiving the award, to receive funding for years 2 and 3. If passing a qualifying exam is not an institutional requirement, then the applicant must have been doing research in the adviser’s lab for at least the 6 months prior to the application deadline and must provide: (1) Institutional proof of acceptance to the PhD program; and (2) a letter from the adviser stating that the student will be supported by the adviser until completion of the student’s PhD degree (or equivalent). The research proposal must focus on projects that fall within FARA’s Research Priorities. Preliminary data are encouraged but not required. Applicants are required to submit a personal statement describing their plans for the future as it relates to FA research, with a description of career goals and how the proposed research and research environment will favor achieving those goals. A mentoring plan developed jointly by the graduate student and the primary research mentor, as well as a mentor’s letter of support are also required. The only allowable budget items are the graduate student’s salary/stipend plus applicable fringe benefits (including health insurance) and tuition costs and fees that are not already covered by the institution. The majority of the student’s time should be dedicated to this project. Recipients of this Fellowship are encouraged to attend the International Congress for Ataxia Research, and FARA will facilitate their participation.

Eligibility

  • Individuals must be enrolled full-time in a research-based (dissertation-required) program, leading to a Ph.D. (or equivalent) at a not-for-profit U.S. or foreign institution of higher education at the time of application. Applicants must be matriculated in the chosen graduate school and have a chosen thesis adviser.
  • Proof of passing qualifying exam, if applicable, is required at the time of application or must be provided within a year of receiving the award to receive funding for years 2 and 3.
  • If passing a qualifying exam is not an institutional requirement, then the applicant must have been doing research in the adviser’s lab for at least the 6 months prior to the application deadline.
  • Individuals must be enrolled full-time and may not accept full-time teaching or research assistantships or internships during fellowship tenure.
  • May not be a recipient of another fellowship / studentship / scholarship, or a previous recipient of this fellowship.
  • Must remain in good academic standing per guidelines of the chosen graduate program.
  • This fellowship can support the Ph.D. portion of an M.D./Ph.D. joint program, if this is not already supported through institutional funds.

Maximum Budget (USD): $50,000 per year, up to 3 years

Deadlines and Important Dates:

  • Letter of Intent (LOI) Deadline: March 15
  • Application Deadline: May 15
  • Award Notice: September 1
  • Grant Start Dates: Oct. 1 – Nov. 1
FUNDED GRANTS

Graduate Research Fellowship

FUNDED GRANT
| Jan 2024

Deciphering the neurodevelopmental component in Friedreich Ataxia

Graduate Research Fellowship, Mechanism or Pathway of Disease Lucie Hermet,
Institute NeuroMyoGène, Lyon, France
FUNDED GRANT
| Sep 2023

Elucidation of the peripheral immune axis in FRDA and identification of blood-based biomarkers of inflammation

Graduate Research Fellowship, Outcome Measures & Biomarkers Shweta Sahni,
All India Institute of Medical Sciences (AIIMS), New Delhi
FUNDED GRANT
| Sep 2023

Population and cellular heterogeneity in Friedreich Ataxia

Graduate Research Fellowship, Mechanism or Pathway of Disease Morgan Tackett,
University of Oklahoma Health Sciences Center
FUNDED GRANT
| Sep 2023

Investigating the effects of frataxin deficiency on the human proteome

Graduate Research Fellowship, Mechanism or Pathway of Disease Angela Xiong,
Boston College

Request for Proposals and Ad-hoc Requests

All RFPs will be announced through this webpage and through our e-bulletin list. If you are not a subscriber please click below to sign-up. Lastly, FARA is willing to consider ad-hoc proposals off cycle that are high-value projects. For more information, please contact FARA at grants@curefa.org