News & Blog

Activation of the ZBP1–cGAS–STING–Type I Interferon Axis as a Mechanistic Driver of Cardiomyopathy in Friedreich’s Ataxia 

Investigating spinal sensory-motor circuit pathology in two mouse models of FA

Inhibition of the TLR4 receptor prevents neuro-inflammation and degeneration in frataxin-deficient sensory neurons

Design and synthesis of SynGR library to probe into the role of NSD-2,3 proteins in FXN expression in FRDA

Understanding the Pathogenesis of Friedreich’s Ataxia by Single-Cell Integration of Gene Expression, Epigenetics and Connectivity in the Cerebellar Nuclei

Characterization of FA iPSC-derived DRG organoid to decipher neurodevelopmental and neurodegenerative mechanisms

Dysregulated microglial Ca2+ homeostasis as a pathogenic contributor and therapeutic target in Friedreich’s ataxia

Developing and delivering of novel gene editing technologies to contract GAA repeats in Friedreich’s ataxia

Anatomical and functional analysis of corticospinal tract in FRDA mouse model

Investigating the Mechanosensory System in Friedreich’s Ataxia using Stem Cell Models

Illuminating how SynGRs liberate gene expression from heterochromatin

Engineering adeno-associated viral vectors to evade immune responses