Defining new epigenetic gene silencing axis driving repeat-associated heterochromatin formation in Friedreich’s Ataxia patients’ cells
Investigating molecular mechanisms underlying microglia hyperactivation in Friedreich Ataxia
Activation of the ZBP1–cGAS–STING–Type I Interferon Axis as a Mechanistic Driver of Cardiomyopathy in Friedreich’s Ataxia
SHIFT-FA – Study of Heterogeneity in Friedreich’s Ataxia Trajectories
Investigating spinal sensory-motor circuit pathology in two mouse models of FA
Correcting Cell-Autonomous Neuroinflammatory Phenotypes in Friedreich’s Ataxia Microglia Using iPSC-Based Approaches
Exploiting Time-Specific Frataxin Inactivation to Unravel Its Role in Peripheral Neurodegeneration in Friedreich Ataxia
Structural Dynamics of the Iron-Sulfur Cluster Assembly Machinery in Patient-Derived FRDA Cells Using Super-Resolution Microscopy
Organelle-Specific Proteomic Profiling to Elucidate Mitochondrial Dysfunction and Therapeutic Mitochondrial Transfer in Friedreich’s Ataxia
Investigating satellite glial cell phenotypes and functions in the pathogenesis of Friedreich’s ataxia
Discovery of genetic suppressor mutations that rescue frataxin deficiency
Exploring the Role of Extracellular Traps in the Pathogenesis of Friedreich’s Ataxia