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FARAFARA Cure FA

Friedreich ataxia: metal dysmetabolism in dorsal root ganglia

Friedreich ataxia (FA) causes distinctive lesions of dorsal root ganglia (DRG), including neuronal atrophy, satellite cell hyperplasia, and absorption of dying nerve cells into residual nodules. Two mechanisms may be involved: hypoplasia of DRG neurons from birth and superimposed iron (Fe)- and zinc (Zn)-mediated oxidative injury.

Read More: Friedreich ataxia: metal dysmetabolism in dorsal root ganglia


About the Author

Jen Farmer

Jen Farmer

Executive Director

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