What the reader will gain: This review covers the most relevant aspects related with the therapeutic use of CoQ10, including existing formulations and their effects on its bioavailability.

Take home message: CoQ10 does not cause serious adverse effects in humans and new formulations have been developed that increase CoQ10 absorption. Oral CoQ10 is a viable antioxidant strategy in many diseases, providing a significant to mild symptomatic benefit. Idebenone and MitoQ are promising substitutive CoQ10-related drugs which are well tolerated and safe.

Read More: Therapeutic use of coenzyme Q(10) and coenzyme Q(10)-related compounds and formulations