Organelle-Specific Proteomic Profiling to Elucidate Mitochondrial Dysfunction and Therapeutic Mitochondrial Transfer in Friedreich’s Ataxia
Unravelling cell type sensitivity to frataxin depletion versus partial frataxin dysfunction using zebrafish models
Investigating satellite glial cell phenotypes and functions in the pathogenesis of Friedreich’s ataxia
Discovery of genetic suppressor mutations that rescue frataxin deficiency
Pre-clinical assessment of protein replacement therapy in the central nervous system of Friedreich’s ataxia mouse models
Advancing FA Treatment: Exploring the Pharmacology of Neonatal Cardiac Progenitor Cells for Cardiac and Neuroprotection
Exploring the Role of Extracellular Traps in the Pathogenesis of Friedreich’s Ataxia
Does Frataxin Deficiency Disrupt GluR2 Trafficking in the Cerebellum via Defects in Palmitoylation?
Leveraging Real-World Data to Define Clinical Milestones and Assess Pharmacologic Impact in Friedreich’s Ataxia Progression
Preclinical evaluation of novel targets for FRDA cardiomyopathy
Lipidomic profiling and analyses of Friedreich’s Ataxia iPSC-derived dorsal root ganglia sensory neurons
Histone H3 Enzyme Activity as a Regulator of Iron-Sulfur Cluster Stability in Friedreich’s Ataxia