Genomics. 2015 Jun 20. pii: S0888-7543(15)30014-8. doi: 10.1016/j.ygeno.2015.06.010. [Epub ahead of print]
Although there have been many investigations into how trinucleotide repeats affect nucleosome formation and local chromatin structure, the nucleosome positioning of GAA triplet-repeats in the human genome has remained elusive. In this work, the nucleosome occupancy around GAA triplet-repeats across the human genome was computed statistically. The results showed a nucleosome-depleted region in the vicinity of GAA triplet-repeats in activated and resting CD4+ T cells.
Read More: GAA triplet-repeats cause nucleosome depletion in the human genome
